👤 Adult

Entacapone

13 known interactions

2 brand names

Indications

Adjunct to co-beneldopa or co-careldopa in Parkinson's disease with ‘end-of-dose’ motor fluctuations (under expert supervision)

Drug Interactions

Moderate interactions

13 drug interactions identified for Entacapone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available

🤱Breastfeeding guidance available

🫁Hepatic impairment guidance

Cautions

Concurrent levodopa dose may need to be reduced by about 10–30%; ischaemic heart disease...

Side Effects

Common or very common Abdominal pain; confusion; constipation; diarrhoea; dizziness; dry mouth; fall; fatigue; hallucination; hyperhidrosis; ischaemic heart disease; movement disorders; nausea; sleep ...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Entacapone(IN)Comtan(IN, PK, SA, AE, EG, ZA, NG)

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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