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👤 Adult👶 Paediatric

Dolutegravir

13 known interactions (4 severe)
2 brand names

Indications

  • HIV infection without resistance to other inhibitors of HIV integrase [in combination with other antiretroviral drugs] (specialist use only)
  • HIV infection in patients with resistance to other inhibitors of HIV integrase [in combination with other antiretroviral drugs] (specialist use only)
  • HIV infection [in combination with other antiretroviral drugs (with concomitant carbamazepine, efavirenz, etravirine (without boosted protease inhibitors, but see also Interactions), fosphenytoin, phenobarbital, phenytoin, primidone, nevirapine, oxcarbazepine, St John's wort, or rifampicin)] (specialist use only)

Drug Interactions

4 SevereModerate interactions

13 drug interactions identified for Dolutegravir. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🫁Hepatic impairment guidance

Side Effects

Common or very common Anxiety; depression; diarrhoea; dizziness; fatigue; flatulence; gastrointestinal discomfort; headache; nausea; skin reactions; sleep disorders; vomiting Uncommon Arthralgia; hepa...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Tivicay(IN, PK, SA, AE, EG, ZA, NG)Dolutegravir(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
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  • CME/CPD tracking
  • 40 language support
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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