MedNext AcademyMedNext
👤 Adult

Dexrazoxane

10 known interactions (1 severe)
2 brand names

Indications

  • Prevention of chronic cumulative cardiotoxicity caused by doxorubicin or epirubicin treatment in advanced or metastatic breast cancer patients who have received a prior cumulative dose of 300 mg/m² of doxorubicin or a prior cumulative dose of 540 mg/m² of epirubicin when further anthracycline treatment is required
  • Anthracycline extravasation

Drug Interactions

1 SevereModerate interactions

10 drug interactions identified for Dexrazoxane. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

Check Interactions in App

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Myelosuppression (effects may be additive to those of chemotherapy) Cautions For Cardioxane® Heart failure—no information available; myocardial infarction in previous 12 months—no information availabl...

Side Effects

Common or very common Alopecia; anaemia; appetite decreased; asthenia; constipation; cough; diarrhoea; dizziness; drowsiness; dry mouth; dyspnoea; embolism and thrombosis; fever; gastrointestinal disc...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Dexrazoxane(IN)Savene(IN, PK, SA, AE, EG, ZA, NG)
Mn

Get the Full Monograph

Complete dosing, interactions, contraindications, side effects, and more for Dexrazoxane.

Download Free — 7-Day Trial

No credit card required

AES-256 EncryptedNo Patient Data

In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

Access all 2866 drugs in the MedNext app

Complete monographs, AI-powered search, interaction checker, dosing calculators, and CME tracking — in 40 languages.

Download MedNext — Free 7-Day Trial