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👤 Adult👶 Paediatric

Cyclophosphamide

18 known interactions
2 brand names

Indications

  • Rheumatoid arthritis with severe systemic manifestations (under expert supervision)
  • Severe systemic rheumatoid arthritis (under expert supervision), Other connective tissue diseases (especially with active vasculitis) (under expert supervision)
  • Malignant disease (specialist use only)

Drug Interactions

Moderate interactions

18 drug interactions identified for Cyclophosphamide. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Avoid in Acute porphyrias ; diabetes mellitus; haemorrhagic cystitis; previous or concurrent mediastinal irradiation—risk of cardiotoxicity...

Side Effects

General side-effects: Common or very common Agranulocytosis; alopecia; anaemia; asthenia; bone marrow disorders; cystitis; decreased leucocytes; fever; haemolytic uraemic syndrome; haemorrhage; hepati...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Endoxan(IN, PK, SA, AE, EG, ZA, NG)Cyclophosphamide(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
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  • CME/CPD tracking
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  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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