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👤 Adult👶 Paediatric

Co-careldopa

2 brand names

Indications

  • Parkinson's disease
  • Parkinson's disease—alternative regimen
  • Parkinson's disease (patients not receiving levodopa/dopa-decarboxylase inhibitor preparations, expressed as levodopa)
  • Parkinson's disease (patients transferring from immediate-release levodopa/dopa-decarboxylase inhibitor preparations)
  • Severe Parkinson's disease inadequately controlled by other preparations

+ 2 more indications in the full monograph

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

-careldopa Acute stroke; Cushing's syndrome; diabetes mellitus; endocrine disorders; history of convulsions; history of myocardial infarction with residual arrhythmia; history of peptic ulcer; hyperth...

Side Effects

-careldopa Rare or very rare Drowsiness; seizure; sudden onset of sleep (can occur without warning) Frequency not known Agranulocytosis; alertness decreased; alopecia; anaemia; angioedema; anxiety; ap...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Syndopa(IN)Sinemet(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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