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👤 Adult👶 Paediatric

Clozapine

39 known interactions (1 severe)
2 brand names

Indications

  • Schizophrenia in patients unresponsive to, or intolerant of, conventional antipsychotic drugs
  • Psychosis in Parkinson's disease

Drug Interactions

1 SevereModerate interactionsMinor interactions

39 drug interactions identified for Clozapine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

antipsychotic drugs Blood dyscrasias; cardiovascular disease; conditions predisposing to seizures; depression; diabetes (may raise blood glucose); epilepsy; history of jaundice; myasthenia gravis; Par...

Side Effects

antipsychotic drugs Common or very common Agitation; amenorrhoea; arrhythmias; constipation; dizziness; drowsiness; dry mouth; erectile dysfunction; fatigue; galactorrhoea; gynaecomastia; hyperglycaem...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Clozaril(IN, PK, SA, AE, EG, ZA, NG)Sizopin(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
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  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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