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👤 Adult👶 Paediatric

Chlorpromazine Hydrochloride

20 known interactions (1 severe)
1 brand name

Indications

  • Schizophrenia and other psychoses, Mania, Short-term adjunctive management of severe anxiety, Psychomotor agitation, excitement, and violent or dangerously impulsive behaviour
  • Intractable hiccup
  • Relief of acute symptoms of psychoses (under expert supervision)
  • Nausea and vomiting in palliative care (where other drugs have failed or are not available)

Drug Interactions

1 SevereModerate interactions

20 drug interactions identified for Chlorpromazine Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

antipsychotic drugs Blood dyscrasias; cardiovascular disease; conditions predisposing to seizures; depression; diabetes (may raise blood glucose); epilepsy; history of jaundice; myasthenia gravis; Par...

Side Effects

antipsychotic drugs Common or very common Agitation; amenorrhoea; arrhythmias; constipation; dizziness; drowsiness; dry mouth; erectile dysfunction; fatigue; galactorrhoea; gynaecomastia; hyperglycaem...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Largactil(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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