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👤 Adult👶 Paediatric

Bupivacaine Hydrochloride

14 known interactions (1 severe)
2 brand names

Indications

  • Surgical anaesthesia, lumbar epidural block
  • Surgical anaesthesia, field block
  • Surgical anaesthesia, thoracic epidural block
  • Surgical anaesthesia, caudal epidural block
  • Surgical anaesthesia, major nerve block

+ 6 more indications in the full monograph

Drug Interactions

1 SevereModerate interactions

14 drug interactions identified for Bupivacaine Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrochloride Cardiovascular disease; cerebral atheroma; complete heart block; debilitated patients (consider dose reduction); elderly (consider dose reduction); epilepsy; hypertension; hypotension; h...

Side Effects

hydrochloride Common or very common Arrhythmias; dizziness; hypertension; hypotension; nausea; paraesthesia; urinary retention; vomiting Uncommon Neurotoxicity Rare or very rare Arachnoiditis; cardiac...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Marcaine(IN, PK, SA, AE, EG, ZA, NG)Sensorcaine(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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