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👤 Adult👶 Paediatric

Azathioprine

26 known interactions (3 severe)
2 brand names

Indications

  • Severe acute Crohn's disease, Maintenance of remission of Crohn's disease, Maintenance of remission of acute ulcerative colitis
  • Rheumatoid arthritis that has not responded to other disease-modifying drugs, Severe systemic lupus erythematosus and other connective tissue disorders, Polymyositis in cases of corticosteroid resistance
  • Autoimmune conditions
  • Suppression of transplant rejection
  • Severe refractory eczema, normal or high TPMT activity

+ 2 more indications in the full monograph

Drug Interactions

3 SevereModerate interactions

26 drug interactions identified for Azathioprine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Reduce dose in elderly; reduced thiopurine methyltransferase activity...

Side Effects

General side-effects: Common or very common Bone marrow depression (dose-related); increased risk of infection; leucopenia; pancreatitis; thrombocytopenia Uncommon Anaemia; hepatic disorders; hypersen...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Imuran(IN, PK, SA, AE, EG, ZA, NG)Azoran(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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