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👤 Adult👶 Paediatric

Atovaquone With Proguanil Hydrochloride

2 brand names

Indications

  • Prophylaxis of falciparum malaria, particularly where resistance to other antimalarial drugs suspected [using 250 mg/100 mg tablets]
  • Prophylaxis of falciparum malaria, particularly where resistance to other antimalarial drugs suspected [using 62.5 mg/25 mg tablets]
  • Treatment of acute uncomplicated falciparum malaria [using 250 mg/100 mg tablets], Treatment of non-falciparum malaria [using 250 mg/100 mg tablets]

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
⚠️Requires renal dose adjustment

Cautions

with proguanil hydrochloride Diarrhoea or vomiting (reduced absorption of atovaquone); efficacy not evaluated in cerebral or complicated malaria (including hyperparasitaemia, pulmonary oedema or renal...

Side Effects

with proguanil hydrochloride Common or very common Abdominal pain; appetite decreased; cough; depression; diarrhoea; dizziness; fever; headache; nausea; skin reactions; sleep disorders; vomiting Uncom...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Malarone(IN, PK, SA, AE, EG, ZA, NG)Malabar(IN)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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