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👤 Adult

Apremilast

12 known interactions
1 brand name

Indications

  • Active psoriatic arthritis (in combination with disease-modifying antirheumatic drugs or alone) in patients who have had an inadequate response or who have been intolerant to a prior disease-modifying antirheumatic drug therapy, Moderate to severe chronic plaque psoriasis that has not responded to standard systemic treatments or photochemotherapy, or when these treatments cannot be used because of intolerance or contra-indications

Drug Interactions

Moderate interactions

12 drug interactions identified for Apremilast. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
⚠️Requires renal dose adjustment

Cautions

Concomitant use of drugs likely to cause psychiatric symptoms; history of psychiatric illness; low body-weight—consider discontinuation if weight loss is unexplained or clinically significant...

Side Effects

Common or very common Appetite decreased; back pain; cough; depression; diarrhoea; fatigue; gastrointestinal discomfort; gastrointestinal disorders; headaches; increased risk of infection; insomnia; n...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Otezla(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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