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👤 Adult👶 Paediatric

Amphotericin B

8 known interactions (1 severe)
2 brand names

Indications

  • Systemic fungal infections
  • Severe systemic or deep mycoses (including disseminated candidiasis and aspergillosis)
  • Mucormycosis
  • Suspected or confirmed fungal infection in febrile neutropenic patients unresponsive to broad-spectrum antibacterials and where investigations have failed to define a bacterial or viral cause
  • Visceral leishmaniasis (unresponsive to the antimonial alone) (under expert supervision)

+ 1 more indication in the full monograph

Drug Interactions

1 SevereModerate interactions

8 drug interactions identified for Amphotericin B. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
⚠️Requires renal dose adjustment

Cautions

B Infusion-related reactions Cautions, further information Infusion-related reactions Infusion-related reactions can be managed by stopping the infusion and restarting at a slower rate (over at least ...

Side Effects

B Common or very common With intravenous use Anaemia; appetite decreased; azotaemia; chills; diarrhoea; dyspnoea; electrolyte imbalance; fever; headache; hepatic function abnormal (discontinue); hypos...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Fungizone(IN, PK)AmBisome(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

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  • Full interaction details & severity
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  • All 2 brand names
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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