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👤 Adult👶 Paediatric

Amitriptyline Hydrochloride

20 known interactions
5 brand names

Indications

  • Abdominal pain or discomfort (in patients who have not responded to laxatives, loperamide, or antispasmodics)
  • Major depressive disorder [not recommended—increased risk of fatality in overdose]
  • Major depressive disorder in patients with cardiovascular disease [not recommended—increased risk of fatality in overdose]
  • Neuropathic pain, Migraine prophylaxis, Chronic tension-type headache prophylaxis
  • Emotional lability in multiple sclerosis

Drug Interactions

Moderate interactions

20 drug interactions identified for Amitriptyline Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

hydrochloride Cardiovascular disease; chronic constipation; diabetes; epilepsy; history of bipolar disorder; history of psychosis; hyperthyroidism (risk of arrhythmias); increased intra-ocular pressur...

Side Effects

hydrochloride Common or very common Accommodation disorder; anxiety; arrhythmias; behaviour abnormal; cardiac conduction disorders; concentration impaired; confusion; constipation; dizziness; drowsine...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Tryptomer(IN)Elavil(IN)+ 3 more in app
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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