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👤 Adult👶 Paediatric

Allopurinol

24 known interactions (1 severe)
2 brand names

Indications

  • Prophylaxis of gout and of uric acid and calcium oxalate renal stones, Prophylaxis of hyperuricaemia associated with cancer chemotherapy
  • Prophylaxis of gout and of uric acid and calcium oxalate renal stones (usual maintenance in mild conditions), Prophylaxis of hyperuricaemia associated with cancer chemotherapy (usual maintenance in mild conditions)
  • Prophylaxis of gout and of uric acid and calcium oxalate renal stones (usual maintenance in moderately severe conditions), Prophylaxis of hyperuricaemia associated with cancer chemotherapy (usual maintenance in moderately severe conditions)
  • Prophylaxis of gout and of uric acid and calcium oxalate renal stones (usual maintenance in severe conditions), Prophylaxis of hyperuricaemia associated with cancer chemotherapy (usual maintenance in severe conditions)

Drug Interactions

1 SevereModerate interactions

24 drug interactions identified for Allopurinol. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Ensure adequate fluid intake (2–3 litres/day); for hyperuricaemia associated with cancer therapy, allopurinol treatment should be started before cancer therapy; thyroid disorders Cautions, further inf...

Side Effects

Common or very common Rash (discontinue therapy; if rash mild re-introduce cautiously but discontinue immediately if recurrence) Uncommon Hypersensitivity; nausea; vomiting Rare or very rare Agranuloc...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Zyloric(IN, PK, SA, AE, EG, ZA, NG)Allopurinol(IN)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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